At this time, there are two kinds of scientific studies on itaconate: Irg1−/− macrophages and also the regulatory outcome of itaconate derivatives. Both of these final results were complementary and discovered the regulatory mechanisms of itaconate involved alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription component 3 https://derekp887cny0.blog-ezine.com/profile