Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other indicators from the microenvironment and escalating the activation of anti-apoptotic and proliferation pathways.31,32 Genomic scientific tests have discovered recurrent mutations in genes regulating tumor mobile-microenvironment ... https://alexm429hpx7.blogscribble.com/profile