Pentobarbital will lower the level or result of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known. pentobarbital will decrease the extent or result of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Observe clients previously on buprenorphine subdermal implant ... https://bonot987ixl4.jasperwiki.com/user